Marmaduke the world's most lovable Great Dane leaps from comic strip fame (appearing in six hundred newspapers in over twenty countries) to big screen stardom in this family comedy event. A suburban family moves to a new neighborhood in Orange County California with their large yet lovable Great Dane who has a tendency to wreak havoc in his own oblivious way. But it's not all living large for the Duke who finds that fitting in with his new four-legged friends and a potential romantic interest isn't always easy for a super-sized teenage dog. Owen Wilson gives the beloved Great Dane his voice in the film which also features the voices of Fergie George Lopez Emma Stone and Kiefer Sutherland.